Designing for a New Era in Biomanufacturing
The biologics industry is rapidly growing, driven by shortened regulatory cycles for drug approvals during the pandemic and increased investment in personalized medicine. This has led to a surge in demand for cell and gene therapy facilities, essential for manufacturing advanced therapies and conducting early-stage clinical trials.
In his whitepaper, “Designing for a New Era in Biomanufacturing,” Som Bose, principal planner at HDR, explores key planning and design strategies for this emerging typology:
Modularity and Flexibility Tailored for Production
Modularity and flexibility are crucial for CGT facilities to accommodate different production workflows, particularly during pandemics when production volumes may surge.
Efficiencies of the Technology Platform
CGT companies often manufacture multiple products. Multiuse platforms with adjacent process suites and closed-loop technologies enable seamless product transfer and simplify product changeover.
Infrastructure and Workflow Optimization
The trend towards single-use technologies allows for mobile lab equipment and integrated solutions that enhance product quality and reduce risks by simplifying operations.
Ergonomics and Human Safety
The unique working environment in pharmaceutical research and manufacturing can lead to musculoskeletal disorders among staff. Ergonomic solutions and adaptable casework solutions offer flexibility and promote staff wellness.
Collaboration and Communication Spaces: Fostering Community and Comfort
Collaborative zones foster interdisciplinary interactions, support innovation and promote teamwork. Design elements like natural daylight, color selection and technology enhance these zones, while strategic placement of collaborative zones builds a sense of community.
From facility planning and design to technology and workflows, ensuring biomanufacturing laboratories are prepared for the increasing development of biologics is crucial. Designing with inherent flexibility and focusing on human comfort will establish resiliency in the typology and improve the workplace environment for staff.
